Semaglutide
Synthetic 31-amino-acid analogue of human GLP-1 with Aib8 and Arg34 substitutions, acylated at Lys26.
From€229
€22.90 per vial · box of ten
In stock
Nova Peptides
Retatrutide
Synthetic lipidated peptide (LY3437943), a GIP, GLP-1 and glucagon receptor triple agonist.
Flat €25 shipping worldwide · free from €600 until 8 Nov.
In stock
One box = ten vials. Single vials are not sold.
Description
Retatrutide is supplied as a lyophilised powder for in vitro and laboratory research. Each box contains ten vials of the strength you select.
Every batch is produced under controlled laboratory conditions.
Vials are shipped lyophilised and are stable at room temperature during transit. For longer storage, keep vials sealed at -20 °C and protected from light. Once reconstituted, store refrigerated and use within the period your protocol specifies.
This product is supplied strictly for laboratory research use. It is not a drug, food or cosmetic, is not approved by any medicines agency, and is not intended for human or animal consumption, nor for diagnostic or therapeutic use.
References
Published, peer-reviewed research on this substance. The papers are about the substance itself and are not statements about this product.
Clinical trials
- Jastreboff AM, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial. The New England journal of medicine. 2023. doi:10.1056/NEJMoa2301972 · PMID 37366315
- Rosenstock J, et al. Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA. Lancet (London, England). 2023. doi:10.1016/S0140-6736(23)01053-X · PMID 37385280
- Coskun T, et al. Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial. The lancet. Diabetes & endocrinology. 2025. doi:10.1016/S2213-8587(25)00092-0 · PMID 40609566
- Giblin K, et al. Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials. Diabetes, obesity & metabolism. 2026. doi:10.1111/dom.70209 · PMID 41090431
Pharmacology and receptor biology
- Li W, et al. Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide. Cell discovery. 2024. doi:10.1038/s41421-024-00700-0 · PMID 39019866
Reviews and meta-analyses
- Pasqualotto E, et al. Effects of once-weekly subcutaneous retatrutide on weight and metabolic markers: A systematic review and meta-analysis of randomized controlled trials. Metabolism open. 2024. doi:10.1016/j.metop.2024.100321 · PMID 39318607
- Katsi V, et al. Retatrutide-A Game Changer in Obesity Pharmacotherapy. Biomolecules. 2025. doi:10.3390/biom15060796 · PMID 40563436
- Abdul-Rahman T, et al. The power of three: Retatrutide's role in modern obesity and diabetes therapy. European journal of pharmacology. 2024. doi:10.1016/j.ejphar.2024.177095 · PMID 39515565
- Drucker DJ. Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and Obesity. Diabetes care. 2024. doi:10.2337/dci24-0003 · PMID 38843460
- Moiz A, et al. Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes : A Systematic Review of Randomized Controlled Trials. Annals of internal medicine. 2025. doi:10.7326/ANNALS-24-01590 · PMID 39761578
Product details
| Also known as | RT · LY3437943 · triple agonist |
|---|---|
| Purity | ≥ 99% (HPLC) |
| Format | Lyophilised powder |
| Pack size | 10 vials per box |
| Storage | Sealed at -20 °C, protected from light |
| Storage (reconstituted) | 2–8 °C in the sealed vial, protected from light |
| Contents | Ten sealed vials of the same strength |
| Analysis | Batch RT10/2026-01-09-A · 30 June 202699.57 % · RP-HPLC (214 nm), identity by MALDI-MSAll published analysis data |
Working out a dilution? How to reconstitute a peptide · Reconstitution calculator
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Retatrutide